Hydrochloric Acid → HCID 10943925, compound

HRID 1978490Notes

Reaction equation

HRID 1978490 reaction equation
[N:1]1[CH:2]=[C:3]2[N:12]3[C:7](=[CH:8][CH:9]=[CH:10][C:11]=13)[S:6][C:5]([C:13]([O:15]CC)=[O:14])=[CH:4]2.[OH-].[Na+].Cl>C(O)C.O>[N:1]1[CH:2]=[C:3]2[N:12]3[C:7](=[CH:8][CH:9]=[CH:10][C:11]=13)[S:6][C:5]([C:13]([OH:15])=[O:14])=[CH:4]2

Participants

6

Reactant 3

HCID 313Hydrochloric AcidHCID 14798Sodium HydroxideHCID 12038723HCID 12038723, compound

Product 1

HCID 10943925HCID 10943925, compound

Reagents, catalysts & solvents 2

HCID 702EthanolSolventHCID 962WaterSolvent

Procedure

To a solution of 193.69 g of the above ethyl 5-thia-1,8b-diazaacenaphthylene-4-carboxylate in 1 l of ethanol was added a solution of 62.9 g (1.57 mol) of sodium hydroxide in 500 ml of water, and the mixture was stirred at room temperature for 0.5 hour. To this reaction mixture was added about 130 ml of concentrated hydrochloric acid with stirring to bring the pH into the range of 4-5 and the resulting precipitate was recovered by filtration and rinsed with ethanol, acetone, and diethyl ether in that order to provide the title compound.

Workup

  1. stirringwith stirring
  2. filtrationthe resulting precipitate was recovered by filtration
  3. washrinsed with ethanol, acetone, and diethyl ether in that order

Sources & evidence

ORD record
ord-6b8f6e72fec547ecb0c5d15aec05b0c7
Source dataset
uspto-grants-2001_05
Patent number
US06235731B1

Reaction notes

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