Hydrochloric Acid → HCID 70248394, compound

HRID 1978494Notes

Reaction equation

HRID 1978494 reaction equation
[C:1]1([CH2:7][CH2:8][CH2:9][N:10]2[CH2:15][CH2:14][CH:13]([C:16](=[O:31])/[CH:17]=[CH:18]/[C:19]3[S:29][C:28]4[N:30]5[C:21](=[CH:22][N:23]=[C:24]5[CH:25]=[CH:26][CH:27]=4)[CH:20]=3)[CH2:12][CH2:11]2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[ClH:32]>CO>[ClH:32].[ClH:32].[C:1]1([CH2:7][CH2:8][CH2:9][N:10]2[CH2:11][CH2:12][CH:13]([C:16](=[O:31])/[CH:17]=[CH:18]/[C:19]3[S:29][C:28]4[N:30]5[C:21](=[CH:22][N:23]=[C:24]5[CH:25]=[CH:26][CH:27]=4)[CH:20]=3)[CH2:14][CH2:15]2)[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 70247622HCID 70247622, compound

Product 1

HCID 70248394HCID 70248394, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

In 2 ml of methanol was dissolved 0.159 g of (E)-1-[1-(3-phenylpropan-1-yl)piperidin-4-yl]-3-(5-thia-1,8b-diazaacenaphthylen-4-yl)propen-1-one, followed by addition of a stoichiometric excess of methanolic hydrochloric acid, and the mixture was stirred for 10 minutes. This reaction mixture was concentrated and crystallized from ethanol-diethyl ether to provide the title compound.

Workup

  1. concentrationThis reaction mixture was concentrated
  2. customcrystallized from ethanol-diethyl ether

Sources & evidence

ORD record
ord-4b073e624666499ab88da7750cc99b68
Source dataset
uspto-grants-2001_05
Patent number
US06235731B1

Reaction notes

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