反应详情

To the above crude (E)-4-[2-[1-(tert-butoxycarbon-yl)piperidin-4-ylmethanesulfonyl]vinyl]-5-thia-1,8b-diazaacenaphthylene was added 3 ml of concentrated hydrochloric acid, and the mixture was stirred at room temperature for 10 minutes. To this reaction mixture was added ethanol, and the resulting precipitate was recovered by filtration and rinsed serially with ethanol and diethyl ether to provide the title compound.

1. filtrationthe resulting precipitate was recovered by filtration
2. washrinsed serially with ethanol and diethyl ether