Hydrochloric Acid → HCID 21993711, compound

HRID 1978500Notes

Reaction equation

HRID 1978500 reaction equation
C(OC([N:8]1[CH2:13][CH2:12][CH:11]([CH2:14][S:15](/[CH:18]=[CH:19]/[C:20]2[S:30][C:29]3[N:31]4[C:22](=[CH:23][N:24]=[C:25]4[CH:26]=[CH:27][CH:28]=3)[CH:21]=2)(=[O:17])=[O:16])[CH2:10][CH2:9]1)=O)(C)(C)C.[ClH:32]>C(O)C>[ClH:32].[ClH:32].[NH:8]1[CH2:13][CH2:12][CH:11]([CH2:14][S:15](/[CH:18]=[CH:19]/[C:20]2[S:30][C:29]3[N:31]4[C:22](=[CH:23][N:24]=[C:25]4[CH:26]=[CH:27][CH:28]=3)[CH:21]=2)(=[O:17])=[O:16])[CH2:10][CH2:9]1

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 86756772HCID 86756772, compound

Product 1

HCID 21993711HCID 21993711, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

To the above crude (E)-4-[2-[1-(tert-butoxycarbon-yl)piperidin-4-ylmethanesulfonyl]vinyl]-5-thia-1,8b-diazaacenaphthylene was added 3 ml of concentrated hydrochloric acid, and the mixture was stirred at room temperature for 10 minutes. To this reaction mixture was added ethanol, and the resulting precipitate was recovered by filtration and rinsed serially with ethanol and diethyl ether to provide the title compound.

Workup

  1. filtrationthe resulting precipitate was recovered by filtration
  2. washrinsed serially with ethanol and diethyl ether

Sources & evidence

ORD record
ord-9c1b6533d2bb474ebdcd268d739f565c
Source dataset
uspto-grants-2001_05
Patent number
US06235731B1

Reaction notes

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