Hydrochloric Acid → HCID 21994098, compound

Participants

Reaction Steps

Concentrated hydrochloric acid (0.8 ml) was added to a stirred solution of N-[3-[4-(2-phenylethan-1-yl)-2-oxopiperazin-1-yl]propan-1-yl]-5-thia-1,8b-diazaacenaphthylene-4-carboxamide (369 mg, 0.799 mmol) in ethanol (5.0 ml) at room temperature. After stirring at room temperature for 1 hour, the reaction mixture was concentrated in vacuo to give N-[3-[4-(2-phenylethan-1-yl)2-oxopiperazin-1-yl]propan-1-yl]-5-thia-1,8b-diazaacenaphthylene-4-carboxamide dihydrochloride as an orange amorphous powder (424 mg, 99%).

Provenance & Evidence