Diphosgene → HCID 86756863, compound

HRID 1978859Notes

Reaction equation

HRID 1978859 reaction equation
Cl[C:2](OC(Cl)(Cl)Cl)=[O:3].[Cl:9][C:10]1[CH:16]=[CH:15][C:13]([NH2:14])=[CH:12][C:11]=1[CH:17]=[CH:18][C:19]([O:21][CH:22]([Cl:24])[CH3:23])=[O:20]>C1(C)C=CC=CC=1>[Cl:9][C:10]1[CH:16]=[CH:15][C:13]([N:14]=[C:2]=[O:3])=[CH:12][C:11]=1[CH:17]=[CH:18][C:19]([O:21][CH:22]([Cl:24])[CH3:23])=[O:20]

Participants

4

Reactant 2

HCID 10426DiphosgeneHCID 70231582HCID 70231582, compound

Product 1

HCID 86756863HCID 86756863, compound

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

108.8 g of trichloromethyl chloroformate were added to a suspension of 130 g of 4-chloro-3-(α-chloroethoxycarbonylethenyl)-aniline in 1200 ml of toluene. The stirred mixture was refluxed for 16 hours. After the resulting precipitate had been separated off, the solvent was removed under reduced pressure, the residue was stirred with petroleum ether and the precipitate was removed and dried.

Workup

  1. temperatureThe stirred mixture was refluxed for 16 hours
  2. customAfter the resulting precipitate had been separated off
  3. customthe solvent was removed under reduced pressure
  4. customthe precipitate was removed
  5. customdried

Sources & evidence

ORD record
ord-fbe1f424212942fc9af4c4225e567cb9
Source dataset
uspto-grants-2001_05
Patent number
US06239074B1

Reaction notes

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