HCID 53974740, compound → HCID 21202060, compound

HRID 1978874Notes

Reaction equation

HRID 1978874 reaction equation
[OH:1][C:2]1[CH:16]=[CH:15][C:14]([O:17][CH3:18])=[CH:13][C:3]=1[CH:4]=[CH:5][C:6]([O:8][C:9]([CH3:12])([CH3:11])[CH3:10])=[O:7]>CO.[Pd]>[OH:1][C:2]1[CH:16]=[CH:15][C:14]([O:17][CH3:18])=[CH:13][C:3]=1[CH2:4][CH2:5][C:6]([O:8][C:9]([CH3:12])([CH3:11])[CH3:10])=[O:7]

Participants

4

Reactant 1

HCID 53974740HCID 53974740, compound

Product 1

HCID 21202060HCID 21202060, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 887MethanolSolvent

Procedure

A mixture of tert-butyl 2-hydroxy-5-methoxycinnamate (27.5 g, 0.11 mol) and 10% Pd/C (2.6 g) in MeOH (350 mL) under H. pressure (45 psi) was shaken for 8 h and filtered. The filtrate was concentrated to to the titled compound (27 g).

Workup

  1. filtrationfiltered
  2. concentrationThe filtrate was concentrated to to the titled compound (27 g)

Sources & evidence

ORD record
ord-6a046f730cc24ba5b948cdfd292a65d2
Source dataset
uspto-grants-2001_05
Patent number
US06239138B1

Reaction notes

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