Water → HCID 69955337, compound

Participants

Reaction Conditions

Reaction Steps

1.3 g of product of Example 2B (2.55 mmol) are dissolved in 55 ml of THF, 18 ml of water containing 0.33 g of potassium hydroxide are added and the mixture is stirred at 20-25° C. for 5 h. Ice is added and the mixture is acidified to pH=5. It is extracted with CH2Cl2. The extracts are purified by chromatography. 0.55 g obtained. Yld: 44%. Decomposition starting at 225° C.—TLC (DM5): Rf=0.1.

Provenance & Evidence