HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(4'-Methyl-biphenyl-4-yl)-4-oxo-butyric acid, methyl ester → 4-(4'-Methyl-biphenyl-4-yl)-4-oxo-butyric acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(4'-Methyl-biphenyl-4-yl)-4-oxo-butyric acid, methyl ester | HCID 70211563 | — |
| Solvent | Hydrochloric Acid | HCID 313 | — |
| Product | 4-(4'-Methyl-biphenyl-4-yl)-4-oxo-butyric acid | HCID 14116666 | 97.1% |
Reaction Steps
In a manner similar to Example 4, Step (b), 4-(4′-methyl-biphenyl-4-yl)-4-oxo-butyric acid, methyl ester (1.21 g, 0.0043 mol) was refluxed in 6 M aqueous hydrochloric acid to give 1.12 g of 4-(4′-methyl-biphenyl-4-yl)-4-oxo-butyric acid as an off-white solid; mp 183-186° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06239288B1 |
| Source dataset | uspto-grants-2001_05 |
| ORD ID | ord-4eb2ac9da9ee4be18e1ce109d49e32d7 |
| Source note | uspto-grants-2001_05 |