HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(3',4'-Dichloro-biphenyl-4-yl)-4-oxo-butyric acid, methyl ester → 4-(3',4'-Dichloro-4-biphenylyl)-4-oxo-butyric acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(3',4'-Dichloro-biphenyl-4-yl)-4-oxo-butyric acid, methyl ester | HCID 86583519 | — |
| Solvent | Hydrochloric Acid | HCID 313 | — |
| Product | 4-(3',4'-Dichloro-4-biphenylyl)-4-oxo-butyric acid | HCID 18364134 | 98.2% |
Reaction Steps
In a manner similar to Example 4, Step (b), 4-(3′,4′-dichloro-biphenyl-4-yl)-4-oxo-butyric acid, methyl ester (1.360 g, 0.004033 mol) was refluxed in 6 M aqueous hydrochloric acid (25 mL) to give 1.280 g of 4-(3′,4′-dichloro-biphenyl-4-yl)-4-oxo-butyric acid as a white solid; mp 154-156° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06239288B1 |
| Source dataset | uspto-grants-2001_05 |
| ORD ID | ord-c2a639c8107f460fa2ebded1f48cfbf7 |
| Source note | uspto-grants-2001_05 |