反应详情

Acrylonitrile (210 ml) and 40% benzyltrimethylammoniumhydroxide in methanol (1.5 ml) were added to 2-nitrodiphenylamine (100 g), and the mixture was refluxed with heat for one hour. The reaction mixture was concentrated under reduced pressure, and the residue was purified by silica gel column chromatography (n-hexane:ethyl acetate=2:1) to thereby obtain 47.7 g of the titled compound as a red solid.

1. temperaturethe mixture was refluxed
2. temperaturewith heat for one hour
3. concentrationThe reaction mixture was concentrated under reduced pressure
4. customthe residue was purified by silica gel column chromatography (n-hexane:ethyl acetate=2:1)