1-Octanol → HCID 86739747, compound

Participants

Reaction Steps

Together there was stirred methyl (2-aminopyrazin-3-yl)formate (5 g; 0.327 mol) and n-octanol (30 ml), together with sodium methoxide (0.3 g), at 85° C. for 1 hour, then 160° C. for 2 days. The n-octanol was distilled off under vacuum, and the residue was passed through a silica gel column, eluting with dichloromethane, to give the title compound (5.78 g).

Provenance & Evidence