Hydrogen Peroxide → HCID 13646633, compound

HRID 1979737Notes

Reaction equation

HRID 1979737 reaction equation
[CH3:1][S:2][C:3]1[NH:4][CH:5]=[C:6]([C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)[C:7]=1[N+:8]([O-:10])=[O:9].[OH:17]O>C(O)(=O)C>[CH3:1][S:2]([C:3]1[NH:4][CH:5]=[C:6]([C:11]2[CH:12]=[CH:13][CH:14]=[CH:15][CH:16]=2)[C:7]=1[N+:8]([O-:10])=[O:9])=[O:17]

Participants

4

Reactant 2

HCID 784Hydrogen PeroxideHCID 13646632HCID 13646632, compound

Product 1

HCID 13646633HCID 13646633, compoundYield 77.5%

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

2-Methylthio-3-nitro-4-phenylpyrrole (3.00 g, 0.013 mol) was suspended in glacial acetic acid (200 ml), and 30% hydrogen peroxide (1,45 g, 0.013 mol) was added. The mixture was stirred at 80° for five hours, after which the mixture was evaporated to dryness and the solid residue was recrystallised from isopropanol to give 2-methylsulphinyl-3-nitro-4-phenylpyrrole (2.52 g), m.p. 197° dec.

Workup

  1. customafter which the mixture was evaporated to dryness
  2. customthe solid residue was recrystallised from isopropanol

Sources & evidence

ORD record
ord-641779cfee91471295bdf4a7c11998d3
Source dataset
uspto-grants-1984_11
Patent number
US04482563

Reaction notes

Loading…