Hydrochloric Acid → 1-Aminohexan-2-one--hydrogen chloride (1/1)

HRID 1979741Notes

Reaction equation

HRID 1979741 reaction equation
C([NH:4][CH:5]([C:11](=[O:16])[CH2:12][CH2:13][CH2:14][CH3:15])C(OCC)=O)(=O)C.[ClH:17]>>[ClH:17].[NH2:4][CH2:5][C:11](=[O:16])[CH2:12][CH2:13][CH2:14][CH3:15]

Participants

3

Reactant 2

HCID 313Hydrochloric AcidHCID 23325041HCID 23325041, compound

Product 1

HCID 233250431-Aminohexan-2-one--hydrogen chloride (1/1)

Procedure

Ethyl 2-acetamido-3-oxoheptanoate (10.4 g) was hydrolysed by heating under reflux with 50% hydrochloric acid (80 ml) for 9 hours. The mixture was evaporated to dryness to give 1-amino-2-hexanone hydrochloride (5.8 g) as a dark red oil.

Workup

  1. temperatureby heating
  2. customThe mixture was evaporated to dryness

Sources & evidence

ORD record
ord-ba8451dd4f9546408e525011f84e4e5e
Source dataset
uspto-grants-1984_11
Patent number
US04482563

Reaction notes

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