Hydrochloric Acid → HCID 12899415, compound

Participants

Reaction Steps

Then 21 g of thus obtained 8-bromo-5-acetyloxy-3,4-dihydrocarbostyril was dispersed in 150 ml of 8N-hydrochloric acid and was heated under refluxing condition for 3 hours. After the reaction mixture was cooled, the insoluble matters were obtained by filtration, washed with water, dried and recrystallized from methanol-water. 14 Grams of 8-bromo-5-hydroxy-3,4-dihydrocarbostyril was obtained as in the form of colorless needle-like crystals. Melting point: 212°-213° C.

Provenance & Evidence