HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1979788Generated: November 1, 2026
Calcium;dibromide;dihydrate → 3-Methoxymethyl-7-phenoxyacetamido-3-cephem-4-carboxylic acid
https://huagongshe.com/reaction/1979788
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Calcium;dibromide;dihydrate | HCID 21694667 | — |
| Reactant | Sodium 3-acetoxymethyl-7-phenoxyacetamido-3-cephem-4-carboxylate | HCID 23673564 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 3-Methoxymethyl-7-phenoxyacetamido-3-cephem-4-carboxylic acid | HCID 15917684 | 87.7% |
Reaction Steps
2 g of sodium 3-acetoxymethyl-7-phenoxyacetamido-3-cephem-4-carboxylate were dissolved in 20 ml of 50% v/v aqueous methanol, and 20 g of calcium bromide dihydrate were added to the resulting solution. The mixture was then stirred at 70° C. for 50 minutes, after which it was treated as described in Example 2, to give 1.55 g of 3-methoxymethyl-7-phenoxyacetamido-3-cephem-4-carboxylic acid, in the form of a yellow solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US04482710 |
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| Source dataset | uspto-grants-1984_11 |
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| ORD ID | ord-303849b118ef4d16b74be8492ca26c26 |
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| Source note | uspto-grants-1984_11 |
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