1,2-Dichloroethane → 3-Ethyl-1-hydroxy-5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalene

HRID 1979893Notes

Reaction equation

[CH2:1]([C:3]1[CH:4]=[C:5]([OH:9])[CH:6]=[CH:7][CH:8]=1)[CH3:2].[CH:10]1[C:15](O)=[CH:14][CH:13]=[CH:12][C:11]=1[CH3:17].[CH2:18](Cl)CCl>>[CH2:1]([C:3]1[CH:4]=[C:5]([OH:9])[C:6]2[C:11]([CH3:10])([CH3:17])[CH2:12][CH2:13][C:14]([CH3:15])([CH3:18])[C:7]=2[CH:8]=1)[CH3:2]

Participants

Reactant 3

HCID 111,2-Dichloroethane

HCID 342M-Cresol

HCID 121013-Ethylphenol

Product 1

HCID 190951933-Ethyl-1-hydroxy-5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalene

Procedure

Employing the same materials as described in Example 1, Step B, except that 3-ethylphenol was substituted for m-cresol, and the reaction was carried out in ethylene dichloride as solvent, there was obtained 3-ethyl-1-hydroxy-5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalene, 66% theor. GLC purity 99%+, exhibiting the expected spectral data.

Sources & evidence

ORD record: ord-bd5677e159eb4c6486d0a693303633d2
Source dataset: uspto-grants-1984_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04483786

Reaction notes

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