HCID 54072298, compound → HCID 54236657, compound

HRID 1979909Notes

Reaction equation

HRID 1979909 reaction equation
[OH:1][CH2:2][CH2:3][O:4][CH2:5][CH2:6][N:7]1[C:11]([CH3:12])=[CH:10][CH:9]=[C:8]1[CH3:13]>[Pd].C(O)C>[OH:1][CH2:2][CH2:3][O:4][CH2:5][CH2:6][N:7]1[CH:11]([CH3:12])[CH2:10][CH2:9][CH:8]1[CH3:13]

Participants

4

Reactant 1

HCID 54072298HCID 54072298, compound

Product 1

HCID 54236657HCID 54236657, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 702EthanolSolvent

Procedure

The pyrrole, 0.8 mole in 1.2 1 of ethanol, was hydrogenated at 1100 psi H2 for three hours at 100° C. using 5 g of 10% Pd/C. The cooled reaction mixture was filtered and distilled to yield N-(hydroxyethoxyethyl)-2,5-dimethylpyrrolidine (b.p.=80° C. at 0.4 mm).

Workup

  1. customThe cooled reaction mixture
  2. filtrationwas filtered
  3. distillationdistilled

Sources & evidence

ORD record
ord-76bbac2b36554c618839c005f4bca9f5
Source dataset
uspto-grants-1984_11
Patent number
US04483833

Reaction notes

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