HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,6-Difluorobenzoyl isocyanate → 1-(2,6-Difluorobenzoyl)-3-(6-methyl-5-phenyl-2-pyridyl)urea
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,6-Difluorobenzoyl isocyanate | HCID 2733369 | — |
| Reactant | 6-Methyl-5-phenylpyridin-2-amine | HCID 13502855 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | 1-(2,6-Difluorobenzoyl)-3-(6-methyl-5-phenyl-2-pyridyl)urea | HCID 13242653 | — |
Reaction Steps
6-Methyl-5-phenyl-2-pyridylamine (500 mg) and 2,6-difluorobenzoyl isocyanate (650 mg) were reacted in 25 ml ethyl acetate. A precipitate formed which was filtered, dried, and identified as the desired product by NMR, m.p. 206°-208° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04508722 |
| Source dataset | uspto-grants-1985_04 |
| ORD ID | ord-8ff3a61095794189a178b61ee56fcf9f |
| Source note | uspto-grants-1985_04 |