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HRID1980321

反应详情

EQUATION

反应方程式

HRID 1980321 的结构方程式

REACTANTS

反应物

2
结构：O=C=NC(=O)c1c(F)cccc1F
HCID2733369

2,6-difluorobenzoyl isocyanate

C8H3F2NO2

结构：Cc1nc(N)ccc1-c1ccccc1
HCID13502855

6-Methyl-5-phenylpyridin-2-amine

C12H12N2

PRODUCTS

生成物

1
结构：Cc1nc(NC(=O)NC(=O)c2c(F)cccc2F)ccc1-c1ccccc1
HCID13242653

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CCOC(C)=O
溶剂HCID8857

Ethyl acetate

C4H8O2

PROCEDURE

实验过程

6-Methyl-5-phenyl-2-pyridylamine (500 mg) and 2,6-difluorobenzoyl isocyanate (650 mg) were reacted in 25 ml ethyl acetate. A precipitate formed which was filtered, dried, and identified as the desired product by NMR, m.p. 206°-208° C.

WORKUP

后处理

  1. customA precipitate formed which
  2. filtrationwas filtered
  3. customdried