Hydrochloric Acid → 2,3-Dichloro-5-(trichloromethyl)pyridine

HRID 1980410Notes

Reaction equation

HRID 1980410 reaction equation
Br[C:2]1[C:7]([Cl:8])=[CH:6][C:5](C)=[CH:4][N:3]=1.[ClH:10].ClCl.[C:13]([Cl:17])(Cl)([Cl:15])[Cl:14]>>[Cl:10][C:2]1[C:7]([Cl:8])=[CH:6][C:5]([C:13]([Cl:17])([Cl:15])[Cl:14])=[CH:4][N:3]=1

Participants

5

Reactant 4

HCID 313Hydrochloric Acid2×HCID 5943Carbon TetrachlorideHCID 24526ChlorineHCID 126309842-Bromo-3-chloro-5-methylpyridine

Product 1

HCID 946472,3-Dichloro-5-(trichloromethyl)pyridine

Procedure

The product from paragraph (i) (2.9 g) in dry carbon tetrachloride (250 ml) was treated with dry hydrogen chloride to convert it to the hydrochloride. Chlorine was passed through the suspension which was kept at 80° C. and illuminated by an ultra-violet lamp inside the reaction flask. After three hours the solvent was removed, leaving a residue of 2,3-dichloro-5-trichloromethylpyridine.

Workup

  1. customwas kept at 80° C.
  2. customilluminated by an ultra-violet lamp inside the reaction flask
  3. customAfter three hours the solvent was removed

Sources & evidence

ORD record
ord-45c1eddc0c2f4d2693ef59d461c350dd
Source dataset
uspto-grants-1985_04
Patent number
US04508907

Reaction notes

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