Propylamine → HCID 13336535, compound

Participants

Reaction Steps

1.87 g of 2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazole-1-yl methyl)-4-methoxycarbonyl thiazolidine (Compound No. 24) prepared in the same manner as in Working Example 2 and 3.0 g of n-propylamine were dissolved in 20 ml of methanol and reacted at a temperature of 60° C. for 1 hour. After distilling off methanol under reduced pressure, the reaction product was purified by silica gel column chromatography using a solvent mixture of chloroform and ethyl acetate as the developer, whereby 0.8 g of 2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazole-1-yl methyl)-4-(n-propylaminocarbonyl)thiazolidine (Compound No. 46 in Table 1) was obtained.

Provenance & Evidence