Dichloromethane → [5-(1-Methanesulfonyl-1H-pyrazol-4-yl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl]-[4-(2-pyrrolidin-1-yl-ethoxy)-phenyl]-amine

HRID 198054Notes

Reaction equation

HRID 198054 reaction equation
[CH3:30][CH2:31][N:32]([CH2:33][CH3:34])[CH2:35][CH3:36].[CH3:37][S:38]([Cl:39])(=[O:40])=[O:41].[Cl:42][CH2:43][Cl:44].[nH:1]1[n:2][cH:3][c:4](-[c:6]2[cH:7][cH:8][cH:9][c:10]3[n:11]2[n:12][c:13]([NH:15][c:16]2[cH:17][cH:18][c:19]([O:22][CH2:23][CH2:24][N:25]4[CH2:26][CH2:27][CH2:28][CH2:29]4)[cH:20][cH:21]2)[n:14]3)[cH:5]1>>[n:1]1[n:2]([S:38]([CH3:37])(=[O:40])=[O:41])[cH:3][c:4](-[c:6]2[cH:7][cH:8][cH:9][c:10]3[n:11]2[n:12][c:13]([NH:15][c:16]2[cH:17][cH:18][c:19]([O:22][CH2:23][CH2:24][N:25]4[CH2:26][CH2:27][CH2:28][CH2:29]4)[cH:20][cH:21]2)[n:14]3)[cH:5]1

Participants

5

Reactant 4

HCID 6344DichloromethaneHCID 8471TriethylamineHCID 31297Methanesulfonyl chlorideHCID 136146545[5-(1H-Pyrazol-4-yl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl]-[4-(2-pyrrolidin-1-yl-ethoxy)-phenyl]-amine

Product 1

HCID 59589843[5-(1-Methanesulfonyl-1H-pyrazol-4-yl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl]-[4-(2-pyrrolidin-1-yl-ethoxy)-phenyl]-amine

Sources & evidence

ORD record
ord-474fae6e17e0445c9d3300b267987f7d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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