Cyclohexylamine → HCID 20401820, compound

Participants

Reaction Steps

using 21.80 g (0.080 mol) of 1-(2-chloro-3-pyridyl)-5-(chloromethyl)-1H-1,2,4-triazole-3-carboxylic acid and 35.70 g (0.360 mol) of cyclohexylamine there is obtained 5-cyclohexyl-4,5-dihydropyrido[2,3-e][1,2,4]triazolo[1,5-a]pyrazine-2-carboxylic acid and the methyl ester thereof which, after recrystallisation from methylene chloride/isopropanol, melts at 170°-176°.

Provenance & Evidence