Cysteamine → HCID 20402177, compound

HRID 1980704Notes

Reaction equation

HRID 1980704 reaction equation
[CH3:1][N:2]([CH3:13])[C:3]1[O:4][C:5]([C:8](OCC)=O)=[N:6][N:7]=1.B.[NH2:15][CH2:16][CH2:17][SH:18]>>[CH3:13][N:2]([CH3:1])[C:3]1[O:4][C:5]([CH2:8][S:18][CH2:17][CH2:16][NH2:15])=[N:6][N:7]=1

Participants

4

Reactant 3

HCID 6058CysteamineHCID 6331BoraneHCID 3733789HCID 3733789, compound

Product 1

HCID 20402177HCID 20402177, compound

Procedure

When 2-dimethylamino-5-ethoxycarbonyl-1,3,4-oxadiazole [prepared according to the procedure described in Org. Magn. Resonance, 6, 144 (1974)] is hydrolyzed and reduced with borane as described in Example 58, Step A, and then is reacted with cysteamine according to the procedure described in Example 60, Step A, there is produced 2-[(2-dimethylamino-1,3,4-oxadiazol-5-yl)methylthio]ethylamine.

Sources & evidence

ORD record
ord-90657916b28140d0bb6038a59f812d0e
Source dataset
uspto-grants-1985_04
Patent number
US04510309

Reaction notes

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