Methylamine → HCID 20400731, compound

HRID 1980817Notes

Reaction equation

HRID 1980817 reaction equation
Cl[C:2]1[C:3](=[O:16])[NH:4][C:5]2[CH2:6][CH2:7][C:8]3[CH:15]=[CH:14][CH:13]=[CH:12][C:9]=3[C:10]=2[CH:11]=1.[CH3:17][NH2:18]>O>[CH3:17][NH:18][C:2]1[C:3](=[O:16])[NH:4][C:5]2[CH2:6][CH2:7][C:8]3[CH:15]=[CH:14][CH:13]=[CH:12][C:9]=3[C:10]=2[CH:11]=1

Participants

4

Reactant 2

HCID 6329MethylamineHCID 20400735HCID 20400735, compound

Product 1

HCID 20400731HCID 20400731, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

Add 23.1 gm of 2-chloro-5,6-dihydro-benzo[f]quinolin-3(4H)-one to 100 ml of 40% aqueous methylamine and 250 ml of water. Heat the system in a steel bomb at 140° C. for 5 days. Stop the reaction and isolate 2-(N-methylamino)-5,6-dihydro-benzo[f]quinolin-3(4H)-one.

Workup

  1. customthe reaction

Sources & evidence

ORD record
ord-74874d4888f84581a5ddd88074180afa
Source dataset
uspto-grants-1985_04
Patent number
US04511569

Reaction notes

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