Sodium Methoxide → HCID 20400701, compound

HRID 1980818Notes

Reaction equation

HRID 1980818 reaction equation
Cl[C:2]1[C:3](=[O:16])[NH:4][C:5]2[CH2:6][CH2:7][C:8]3[CH:15]=[CH:14][CH:13]=[CH:12][C:9]=3[C:10]=2[CH:11]=1.C[O-:18].[Na+]>CO>[OH:18][C:2]1[C:3](=[O:16])[NH:4][C:5]2[CH2:6][CH2:7][C:8]3[CH:15]=[CH:14][CH:13]=[CH:12][C:9]=3[C:10]=2[CH:11]=1

Participants

4

Reactant 2

HCID 10942334Sodium MethoxideHCID 20400735HCID 20400735, compound

Product 1

HCID 20400701HCID 20400701, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

Add 23.1 gm of 2-chloro-5,6-dihydro-benzo[f]quinolin-3(4H)-one to 300 ml of methanol containing 30 gm of sodium methoxide. Heat the system in a steel bomb at about 200° C. for 12 hours. Stop the reaction, remove solvent, treat with water, and isolate the title compound.

Workup

  1. customthe reaction
  2. customremove solvent
  3. additiontreat with water

Sources & evidence

ORD record
ord-772c0c30718d4c30935a850f1538a678
Source dataset
uspto-grants-1985_04
Patent number
US04511569

Reaction notes

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