Sodium Bicarbonate → HCID 13424125, compound

HRID 1980850Notes

Reaction equation

HRID 1980850 reaction equation
Cl.[N:2]1[CH:7]=[CH:6][CH:5]=[C:4]([C:8]2[NH:9][C:10]3[C:15]([C:16]=2[CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][C:22]([OH:24])=[O:23])=[CH:14][CH:13]=[CH:12][CH:11]=3)[CH:3]=1.C(=O)(O)[O-].[Na+]>>[N:2]1[CH:7]=[CH:6][CH:5]=[C:4]([C:8]2[NH:9][C:10]3[C:15]([C:16]=2[CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][C:22]([OH:24])=[O:23])=[CH:14][CH:13]=[CH:12][CH:11]=3)[CH:3]=1

Participants

3

Reactant 2

HCID 516892Sodium BicarbonateHCID 20400825HCID 20400825, compound

Product 1

HCID 13424125HCID 13424125, compound

Procedure

An aqueous solution of 10.5 g of 2-(3-pyridyl)-3-(5-carboxypentyl)-indole hydrochloride is neutralized to about pH 7 with saturated sodium bicarbonate solution and extracted with ether. The ether extract is dried and concentrated in vacuo to yield 2-(3-pyridyl)-3-(5-carboxypentyl)-indole.

Workup

  1. extractionextracted with ether
  2. extractionThe ether extract
  3. customis dried
  4. concentrationconcentrated in vacuo

Sources & evidence

ORD record
ord-1ec24c4602a94360b9e7699a7ab24b42
Source dataset
uspto-grants-1985_04
Patent number
US04511573

Reaction notes

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