2-Thiocresol → HCID 12963243, compound

HRID 1980883Notes

Reaction equation

HRID 1980883 reaction equation
[Cl:1]N1C(=O)CCC1=O.[C:9]1([CH3:16])[C:10]([SH:15])=[CH:11][CH:12]=[CH:13][CH:14]=1>C1C=CC=CC=1>[C:9]1([CH3:16])[C:10]([S:15][Cl:1])=[CH:11][CH:12]=[CH:13][CH:14]=1

Participants

4

Reactant 2

HCID 87122-ThiocresolHCID 31398Chlorosuccinimide

Product 1

HCID 12963243HCID 12963243, compoundYield 87.1%

Reagents, catalysts & solvents 1

HCID 241BenzeneSolvent2×

Procedure

N-chlorosuccinimide (5.34 g., 40 mmoles) was slurried in 50 ml. of benzene and cooled in an ice-water bath. o-Toluenethiol (4.96 g., 40 mmoles) in 50 ml. of benzene was added dropwise over 15 minutes. The reaction was warmed to room temperature and stirred for approximately 16 hours. The reaction mixture was filtered and o-toluenesulfenyl chloride (5.53 g.) obtained as an oil by evaporation in vacuo.

Workup

  1. filtrationThe reaction mixture was filtered

Sources & evidence

ORD record
ord-10c70f7073f04fe5bb895dc28f4311dc
Source dataset
uspto-grants-1985_04
Patent number
US04511575

Reaction notes

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