2-Thiocresol → HCID 12963243, compound

HRID 1980965Notes

Reaction equation

HRID 1980965 reaction equation
[Cl:1]N1C(=O)CCC1=O.[C:9]1([CH3:16])[C:10]([SH:15])=[CH:11][CH:12]=[CH:13][CH:14]=1>C1C=CC=CC=1>[C:9]1([CH3:16])[C:10]([S:15][Cl:1])=[CH:11][CH:12]=[CH:13][CH:14]=1

Participants

4

Reactant 2

HCID 87122-ThiocresolHCID 31398Chlorosuccinimide

Product 1

HCID 12963243HCID 12963243, compoundYield 87.1%

Reagents, catalysts & solvents 1

HCID 241BenzeneSolvent2×

Procedure

N-chlorosuccinimide (5.34 g., 40 mmoles) was slurried in 50 ml. of benzene and cooled in an ice-water bath. o-Toluenethiol (4.96 g., 40 mmoles) in 50 ml. of benzene was added dropwise over 15 minutes. The reaction was warmed to room temperature and stirred for approximately 16 hours. The reaction mixture was filtered and o-toluenesulfenyl chloride (5.53 g.) obtained as an oil by evaporation in vacuo.

Workup

  1. filtrationThe reaction mixture was filtered

Sources & evidence

ORD record
ord-fbe6050b27f0424998d27eb7f6d35a8f
Source dataset
uspto-grants-1985_04
Patent number
US04511576

Reaction notes

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