2,4-Dichlorobenzoyl chloride → HCID 12897066, compound

HRID 1981004Notes

Reaction equation

HRID 1981004 reaction equation
[Cl:1][C:2]1[CH:10]=[C:9]([Cl:11])[CH:8]=[CH:7][C:3]=1[C:4](Cl)=[O:5].[NH:12]1[CH:16]=[CH:15][C:14]([C:17]([O:19][CH3:20])=[O:18])=[CH:13]1>>[Cl:1][C:2]1[CH:10]=[C:9]([Cl:11])[CH:8]=[CH:7][C:3]=1[C:4]([C:16]1[NH:12][CH:13]=[C:14]([C:17]([O:19][CH3:20])=[O:18])[CH:15]=1)=[O:5]

Participants

3

Reactant 2

HCID 666452,4-Dichlorobenzoyl chlorideHCID 12361759methyl 1H-pyrrole-3-carboxylate

Product 1

HCID 12897066HCID 12897066, compound

Procedure

By the procedure of Example 64, 2,4-dichlorobenzoyl chloride (4.18 g., 20 mmoles) and methyl pyrrole-3-carboxylate were reacted to form methyl 5-(2,4-dichlorobenzoyl)pyrrole-3-carboxylate (3.0 g., gummy solid, Rf 0.5 on silica gel thin layer chromatography with ethyl acetate-1/hexane-1 as eluant).

Sources & evidence

ORD record
ord-4f12574c79234df497c128b2cc350e85
Source dataset
uspto-grants-1985_04
Patent number
US04511576

Reaction notes

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