Hexane → HCID 70410281, compound

HRID 1981069Notes

Reaction equation

HRID 1981069 reaction equation
[CH3:1][N:2]1[C:6]([S:7][CH3:8])=[CH:5][CH:4]=[C:3]1[C:9]([C:11]1[N:15]2[CH2:16][CH2:17][CH:18]([C:19]([OH:21])=[O:20])[C:14]2=[CH:13][C:12]=1[CH3:22])=[O:10].ClC1C=CC=C(C(OO)=[O:31])C=1.CCCCCC>C(Cl)(Cl)Cl.CS(C)=O>[CH3:1][N:2]1[C:6]([S:7]([CH3:8])=[O:31])=[CH:5][CH:4]=[C:3]1[C:9]([C:11]1[N:15]2[CH2:16][CH2:17][CH:18]([C:19]([OH:21])=[O:20])[C:14]2=[CH:13][C:12]=1[CH3:22])=[O:10]

Participants

6

Reactant 3

HCID 8058HexaneHCID 70297m-Chloroperbenzoic acidHCID 13424022HCID 13424022, compound

Product 1

HCID 70410281HCID 70410281, compoundYield 100.6%

Reagents, catalysts & solvents 2

HCID 679Dimethyl SulfoxideCatalystHCID 6212ChloroformSolvent

Procedure

A solution of 0.2 g of 5-(1-methyl-5-methylthio-2-pyrroyl)-1,2-dihydro-6-methyl-3H-pyrrolo-[1,2-a]-pyrrole-1-carboxylic acid in 20 ml chloroform and a few drops of dimethylsulfoxide was treated with 0.1 g of m-chloroperbenzoic acid (MCPBA) and stirred overnight. Hexane was then added carefully, and the mixture was cooled and the resulting yellow crystals was collected by filtration to give 195 mg of 5-(1-methyl-5-methylsulfinyl-2-pyrroyl)-1,2-dihydro-6-methyl-3H-pyrrolo-[1,2-a]pyrrole-1-carboxylic acid. m/e 334.

Workup

  1. temperaturethe mixture was cooled
  2. filtrationthe resulting yellow crystals was collected by filtration

Sources & evidence

ORD record
ord-2fcbcbb985e149cb8bd1840ba6ae1a09
Source dataset
uspto-grants-1985_04
Patent number
US04511724

Reaction notes

Loading…