反应详情

400 ml. of water are added to 143.5 g. of N-(benzyloxy)ethylenediamine dihydrochloride. 207.0 g. of potassium carbonate are gradually added carefully to this suspension. Thereafter, 200 ml. of toluene and then, slowly, 145.7 g. of 2,6-dichlorophenylimidocarbonyl chloride in 100 ml. of toluene are added dropwise in the course of 45 minutes, while stirring vigorously. After 15 minutes, a product begins to separate out. The mixture is further stirred overnight and then poured onto 1 liter of n-hexane. The precipitate is filtered off and washed with water and with n-hexane, whereupon 1-benzyloxy-2-[(2,6-dichlorophenyl)imino]imidazolidine, m.p. 114°-117°, is obtained.

1. customto separate out
2. waitThe mixture is further stirred overnight
3. additionpoured onto 1 liter of n-hexane
4. filtrationThe precipitate is filtered off
5. washwashed with water and with n-hexane, whereupon 1-benzyloxy-2-[(2,6-dichlorophenyl)imino]imidazolidine, m.p. 114°-117°
6. customis obtained