Water → HCID 13472126, compound

Participants

Reaction Steps

The 1-(5-hydroxypentanoyl)-1,2,3,4-tetrahydroquinoline (2.0 g) was refluxed for 8 hours in ether (250 ml) containing lithium aluminium hydride (1.0 g). The solution was cooled, water was added, and the ethereal solution was extracted with dilute hydrochloric acid. The extract was basified with sodium hydroxide and extracted with ether. The ethereal solution was dried and evaporated to afford the title compound as an oil.

Provenance & Evidence