Sulfuric Acid → HCID 20399850, compound

HRID 1981139Notes

Reaction equation

HRID 1981139 reaction equation
C(O)(=O)C.[CH3:5][N:6]([CH3:23])[CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][N:13]1[C:22]2[C:17](=[CH:18][CH:19]=[CH:20][CH:21]=2)[CH2:16][CH2:15][CH2:14]1.[S:24](=[O:28])(=[O:27])([OH:26])[OH:25]>O>[S:24](=[O:26])(=[O:25])([OH:28])[OH:27].[CH3:23][N:6]([CH3:5])[CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][N:13]1[C:22]2[C:17](=[CH:18][CH:19]=[CH:20][CH:21]=2)[CH2:16][CH2:15][CH2:14]1

Participants

4

Reactant 2

HCID 1118Sulfuric AcidHCID 70486795HCID 70486795, compound

Product 1

HCID 20399850HCID 20399850, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

6-dimethylamino-1-(1,2,3,4-tetrahydroquinolin-1-yl)-hexane acetate (1.0 g) is dissolved in 50 ml water containing a stoichiometric equivalent of sulfuric acid, and the solution evaporated to dryness. The product is suspended in ethanol and filtered, air dried and recrystallized from methanol/acetone to yield 6-dimethylamino-1-(1,2,3,4-tetrahydroquinolin-1-yl)-hexane bisulfate.

Workup

  1. customthe solution evaporated to dryness
  2. filtrationfiltered
  3. customair dried
  4. customrecrystallized from methanol/acetone

Sources & evidence

ORD record
ord-a49692d0d02a4e75bdd19ec241475d79
Source dataset
uspto-grants-1985_04
Patent number
US04512990

Reaction notes

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