HuagongsheHuagongshe Chemistry Print Report · For research reference only
(3S)-3-Benzoylamino-1-chloro-4-phenyl-2-butanone → 4-oxo-1,5-benzothiazepine-5(2H)-acetic acid, ethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (3S)-3-Benzoylamino-1-chloro-4-phenyl-2-butanone | HCID 13339657 | — |
| Reactant | (+/-)-3-amino-3,4-dihydro-4-oxo-1,5-benzothiazepine-5(2H)-acetic acid, ethyl ester | HCID 15591257 | — |
| Product | 4-oxo-1,5-benzothiazepine-5(2H)-acetic acid, ethyl ester | HCID 86740033 | — |
Reaction Steps
(±)-3-Amino-3,4-dihydro-4-oxo-1,5-benzothiazepine-5(2H)-acetic acid, ethyl ester is reacted with (S)-N-[3-chloro-2-oxo-1-(phenylmethyl)propyl]benzamide according to the procedure of Example 1(h) to yield (±)-dihydro-3-[[3-benzoylamino)-2-oxo-4-phenylbutyl]amino]-4-oxo-1,5-benzothiazepine-5(2H)-acetic acid, ethyl ester.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04512988 |
| Source dataset | uspto-grants-1985_04 |
| ORD ID | ord-a9ad7b8a8c8a498db8e7835307e2d23c |
| Source note | uspto-grants-1985_04 |