HuagongsheHuagongshe Chemistry Print Report · For research reference only
Glycolic Acid → Oxolan-2-yl bromoacetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Glycolic Acid | HCID 757 | — |
| Reactant | Bromoacetic Acid | HCID 6227 | — |
| Reactant | 2,3-Dihydrofuran | HCID 70934 | — |
| Product | Oxolan-2-yl bromoacetate | HCID 15391487 | — |
Reaction Steps
The glycolic acid derivative is obtained by reacting 6.95 g (0.05 mol) of bromoacetic acid and 2.80 g (0.4 mol) of 2,3-dihydrofuran at room temperature in the absence of moisture, and stirring the mixture after 5 hours (bromoacetic acid is converted quantitatively). This reaction solution was employed in the following synthesis step, without isolation. The glycolic acid derivative has the formula: ##STR6##
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04513004 |
| Source dataset | uspto-grants-1985_04 |
| ORD ID | ord-f946150c48514586b27688c549747d23 |
| Source note | uspto-grants-1985_04 |