HCID 12750043, compound → HCID 12750037, compound

HRID 1981214Notes

Reaction equation

HRID 1981214 reaction equation
[C:1]1(/[CH:7]=[CH:8]\[CH2:9][CH2:10][CH2:11][C:12]([O:14]C)=[O:13])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1>O1CCOCC1.C(=O)([O-])[O-].[Na+].[Na+]>[C:1]1(/[CH:7]=[CH:8]\[CH2:9][CH2:10][CH2:11][C:12]([OH:14])=[O:13])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

Participants

4

Reactant 1

HCID 12750043HCID 12750043, compound

Product 1

HCID 12750037HCID 12750037, compound

Reagents, catalysts & solvents 2

HCID 10340Sodium CarbonateSolventHCID 312751,4-DioxaneSolvent

Procedure

A solution of methyl (Z)-6-phenyl-5-hexenoate (2.0 g) in dioxan (20 ml) and 10% sodium carbonate solution (20 ml) was heated under reflux for 6 hours and evaporated to low volume. The residue was diluted with water, washed with ether, acidified and extracted with ether. The extract was dried and evaporated to give (Z)-6-phenyl-5-hexenoic acid.

Workup

  1. temperatureunder reflux for 6 hours
  2. customevaporated to low volume
  3. additionThe residue was diluted with water
  4. washwashed with ether
  5. extractionextracted with ether
  6. customThe extract was dried
  7. customevaporated

Sources & evidence

ORD record
ord-b23ebd1e3f9048e592eee332bc79c302
Source dataset
uspto-grants-1985_04
Patent number
US04513005

Reaction notes

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