HCID 13105361, compound → HCID 13105328, compound

HRID 1981223Notes

Reaction equation

HRID 1981223 reaction equation
[C:1]1([CH2:7][CH2:8]/[CH:9]=[CH:10]/[CH2:11][CH2:12][CH2:13][C:14]([O:16]C)=[O:15])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1>O1CCOCC1.C(=O)([O-])[O-].[Na+].[Na+]>[C:1]1([CH2:7][CH2:8]/[CH:9]=[CH:10]/[CH2:11][CH2:12][CH2:13][C:14]([OH:16])=[O:15])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

Participants

4

Reactant 1

HCID 13105361HCID 13105361, compound

Product 1

HCID 13105328HCID 13105328, compound

Reagents, catalysts & solvents 2

HCID 10340Sodium CarbonateSolventHCID 312751,4-DioxaneSolvent

Procedure

A stirred solution of methyl (E)-8-phenyl-5-octenoate (13.6 g) in dioxan (125 ml) and 10% sodium carbonate solution (125 ml) was heated under reflux for 7 hours then evaporated. The residue in water was washed with ether, acidified and extracted with ether and the extract was dried and evaporated. The residue was distilled under vacuum to give the title compound, b.p. 150° to 153° C./0.2 mm.

Workup

  1. temperatureunder reflux for 7 hours
  2. customthen evaporated
  3. washThe residue in water was washed with ether
  4. extractionextracted with ether
  5. customthe extract was dried
  6. customevaporated
  7. distillationThe residue was distilled under vacuum

Sources & evidence

ORD record
ord-7c5de03679f14050879128a282db5c5b
Source dataset
uspto-grants-1985_04
Patent number
US04513005

Reaction notes

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