Dimethylamine → 1,3-Dimethyl-1-phenylurea

HRID 1981384Notes

Reaction equation

HRID 1981384 reaction equation
[C:1]([C:5]1ON=[C:7]([C:10]([NH:12][CH:13]=[O:14])=O)[CH:6]=1)([CH3:4])(C)C.CN.[C:17]([NH2:25])(=O)C1C=CC=CC=1.[CH3:26]NC>>[CH3:17][NH:25][C:13]([N:12]([CH3:26])[C:10]1[CH:4]=[CH:1][CH:5]=[CH:6][CH:7]=1)=[O:14]

Participants

5

Reactant 4

HCID 674DimethylamineHCID 2331BenzamideHCID 6329MethylamineHCID 86740066HCID 86740066, compound

Product 1

HCID 703171,3-Dimethyl-1-phenylureaYield 64.7%

Procedure

The procedures of Example 1 were repeated except that (5-t-butyl-3-isooxazoyl)formamide and methylamine were replaced with benzamide and dimethylamine, respectively, to give N,N'-dimethyl-N'-phenylurea in 64.70% yield.

Sources & evidence

ORD record
ord-79e35af8dda94d2499b5ff851b4ad505
Source dataset
uspto-grants-1985_04
Patent number
US04514571

Reaction notes

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