Hydrochloric Acid → HCID 131714201, compound

HRID 1981422Notes

Reaction equation

HRID 1981422 reaction equation
[C:1]([C:3]1[CH:8]=[CH:7][C:6](O)=[C:5]([O:10][CH3:11])[CH:4]=1)#[N:2].[ClH:12].[CH3:13][OH:14]>>[CH3:13][O:14][N:2]=[CH:1][C:3]1[CH:8]=[CH:7][C:6]([Cl:12])=[C:5]([O:10][CH3:11])[CH:4]=1

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 887MethanolHCID 781354-Hydroxy-3-methoxybenzonitrile

Product 1

HCID 131714201HCID 131714201, compound

Procedure

In 50 ml of anhydrous methanol, was dissolved 7.5 g of 4-cyano-2-methoxyphenol. The solution was saturated with dried gaseous hydrogen chloride, while being cooled in ice and stirred, and then stirred overnight at room temperature to precipitate yellow crystals. After addition of ethyl ether, the crystals were collected by filtration, washed with ethyl ether and dried to obtain 9.4 g of 4-methoxyiminomethyl-2-methoxyphenyl hydrochloride.

Workup

  1. temperaturewhile being cooled in ice
  2. stirringstirred overnight at room temperature
  3. customto precipitate yellow crystals
  4. additionAfter addition of ethyl ether
  5. filtrationthe crystals were collected by filtration
  6. washwashed with ethyl ether
  7. customdried

Sources & evidence

ORD record
ord-e0f678a8725541538b15b2d63e314c38
Source dataset
uspto-grants-1985_04
Patent number
US04514416

Reaction notes

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