Acetaldehyde → HCID 13326884, compound

HRID 1981473Notes

Reaction equation

HRID 1981473 reaction equation
O.O[C:3]1(O)[CH:8]=[C:7]([O:9][C:10]2[C:19]3[C:14](=[CH:15][CH:16]=[CH:17][CH:18]=3)[C:13]([Cl:20])=[CH:12][CH:11]=2)[CH:6]=[CH:5][CH:4]1[C:21](=[O:24])[CH:22]=[O:23].O[C:27]1(O)C=C(OC2C3C(=CC=CC=3)C(Cl)=CC=2)C=C[CH:28]1C(=O)C=O.[NH2:50][C:51]1[CH:59]=[CH:58][C:54]([C:55]([OH:57])=[O:56])=[CH:53][CH:52]=1.C(=O)C>>[Cl:20][C:13]1[C:14]2[C:19](=[CH:18][CH:17]=[CH:16][CH:15]=2)[C:10]([O:9][C:7]2[CH:8]=[CH:3][C:4]([C:21](=[O:24])[CH:22]([NH:50][C:51]3[CH:59]=[CH:58][C:54]([C:55]([OH:57])=[O:56])=[CH:53][CH:52]=3)[O:23][CH2:27][CH3:28])=[CH:5][CH:6]=2)=[CH:11][CH:12]=1

Participants

4

Reactant 3

HCID 177AcetaldehydeHCID 9784-Aminobenzoic AcidHCID 88674768HCID 88674768, compound

Product 1

HCID 13326884HCID 13326884, compound

Procedure

A mixture of 4.2 g. of 2,2-dihydroxy-4-(4-chloro-1-naphthyloxy)-α-oxo-benzeneacetaldehyde hemihydrate, 1.76 g. of p-aminobenzoic acid and 30 ml. of absolute ethanal was refluxed overnight under argon. The solid was collected, boiled in ethanol, cooled and filtered, giving the desired product as a pale yellow solid, m.p. 155°-165° C.

Workup

  1. additionA mixture of 4.2 g
  2. customThe solid was collected
  3. temperaturecooled
  4. filtrationfiltered

Sources & evidence

ORD record
ord-0584c366d8e045b9a5e3bf8079abbc21
Source dataset
uspto-grants-1986_06
Patent number
US04592876

Reaction notes

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