Hydrochloric Acid → HCID 23319739, compound

HRID 1981604Notes

Reaction equation

HRID 1981604 reaction equation
[Cl:1][CH2:2][C:3]([N:5]([CH2:15][N:16]1[CH:20]=[N:19][CH:18]=[N:17]1)[C:6]1[C:11]([CH2:12][CH3:13])=[CH:10][CH:9]=[CH:8][C:7]=1[CH3:14])=[O:4].Cl>ClCCl.CCOCC>[ClH:1].[Cl:1][CH2:2][C:3]([N:5]([CH2:15][N:16]1[CH:20]=[N:19][CH:18]=[N:17]1)[C:6]1[C:11]([CH2:12][CH3:13])=[CH:10][CH:9]=[CH:8][C:7]=1[CH3:14])=[O:4]

Participants

5

Reactant 2

HCID 313Hydrochloric AcidHCID 130141922-Chloro-N-(2-ethyl-6-methylphenyl)-N-(1H-1,2,4-triazol-1-ylmethyl)acetamide

Product 1

HCID 23319739HCID 23319739, compound

Reagents, catalysts & solvents 2

HCID 3283Diethyl EtherSolvent2×HCID 6344DichloromethaneSolvent

Procedure

10.0 parts by weight of 2-chloro-2'-methyl-6'-ethyl-N-(1,2,4-triazol-1-yl-methyl)-acetanilide is dissolved in 50 parts by volume of a mixture of anhydrous dichloromethane and ether (1:1). Dry hydrogen chloride is then passed in, while cooling, for 15 minutes, and a further 55 parts by volume of anhydrous ether is dripped in. The precipitated crystals are suction filtered, and there is obtained 7.5 parts by weight of 2-chloro-2'-methyl-6'-ethyl-N-(1,2,4-triazol-1-yl-methyl)acetanilide hydrochloride; m.p.: 148° C.

Workup

  1. temperaturewhile cooling, for 15 minutes
  2. filtrationfiltered

Sources & evidence

ORD record
ord-f8ecc517787f4e23ad618cb693aa637c
Source dataset
uspto-grants-1986_06
Patent number
US04593104

Reaction notes

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