Oxalic Acid → N-[2-(Diethylamino)ethyl]-3-(phenylthio)-1-homopiperidinecarboxamide Oxalate

HRID 1981817Notes

Reaction equation

HRID 1981817 reaction equation
[C:1]([N:8]1[CH:12]=[CH:11][N:10]=[CH:9]1)(N1C=CN=C1)=[O:2].[CH2:13](NN(CC)NCC)[CH3:14].[C:22]1([S:28][CH:29]2[CH2:35][CH2:34][CH2:33][CH2:32][NH:31][CH2:30]2)[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=1.[C:36]([OH:41])(=[O:40])[C:37]([OH:39])=[O:38]>>[C:36]([OH:41])(=[O:40])[C:37]([OH:39])=[O:38].[CH2:13]([N:10]([CH2:9][CH3:36])[CH2:11][CH2:12][NH:8][C:1]([N:31]1[CH2:32][CH2:33][CH2:34][CH2:35][CH:29]([S:28][C:22]2[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=2)[CH2:30]1)=[O:2])[CH3:14]

Participants

5

Reactant 4

HCID 971Oxalic AcidHCID 682631,1'-CarbonyldiimidazoleHCID 202178903-(Phenylthio)homopiperidineHCID 57254831N,N-diethylaminoethylamine

Product 1

HCID 20217798N-[2-(Diethylamino)ethyl]-3-(phenylthio)-1-homopiperidinecarboxamide Oxalate

Procedure

Following the procedure of Example 16, 1,1'-carbonyldiimidazole, N,N-diethylaminoethylamine and 3-(phenylthio)homopiperidine and oxalic acid are reacted to give the title compound.

Workup

  1. customare reacted

Sources & evidence

ORD record
ord-83266f7079a0477dbfb97d0f8671a424
Source dataset
uspto-grants-1986_06
Patent number
US04593102

Reaction notes

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