Ammonia → HCID 23317812, compound

HRID 1981836Notes

Reaction equation

HRID 1981836 reaction equation
[NH3:1].[CH3:2][P:3]([CH3:10])([CH:5]([OH:9])[C:6]([OH:8])=[O:7])=[O:4]>O>[CH3:2][P:3]([CH3:10])([CH:5]([OH:9])[C:6]([O-:8])=[O:7])=[O:4].[NH4+:1]

Participants

4

Reactant 2

HCID 222AmmoniaHCID 119559(Dimethylphosphoryl)(hydroxy)acetic acid

Product 1

HCID 23317812HCID 23317812, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Conditions

Temperature
25 °C

Procedure

10 g of 25% strength aqueous ammonia solution are added dropwise to a solution of 15.2 g (0.1 mol) of 2-(dimethylphosphinoyl)-2-hydroxy-acetic acid in 10 ml of water. The temperature thereby rises to 38°. The mixture is stirred at 25° C. for one hour and concentrated on a rotary evaporator. The residue is first dehydrated azeotropically with toluene and then boiled up with acetonitrile. 14.3 g (84.6%) of the salt of melting point 183°-186° remain.

Workup

  1. customthereby rises to 38°
  2. concentrationconcentrated on a rotary evaporator

Sources & evidence

ORD record
ord-3d7e045d11c14aedafbfe0f8654acd89
Source dataset
uspto-grants-1986_06
Patent number
US04594098

Reaction notes

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