Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Ammonia | HCID 222 | — |
| Reactant | (Dimethylphosphoryl)(hydroxy)acetic acid | HCID 119559 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 23317812 | HCID 23317812 | — |
Reaction Steps
10 g of 25% strength aqueous ammonia solution are added dropwise to a solution of 15.2 g (0.1 mol) of 2-(dimethylphosphinoyl)-2-hydroxy-acetic acid in 10 ml of water. The temperature thereby rises to 38°. The mixture is stirred at 25° C. for one hour and concentrated on a rotary evaporator. The residue is first dehydrated azeotropically with toluene and then boiled up with acetonitrile. 14.3 g (84.6%) of the salt of melting point 183°-186° remain.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US04594098 |
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| Source dataset | uspto-grants-1986_06 |
|---|
| ORD ID | ord-3d7e045d11c14aedafbfe0f8654acd89 |
|---|
| Source note | uspto-grants-1986_06 |
|---|
