Hydrochloric Acid → HCID 178524645, compound

HRID 1981924Notes

Reaction equation

HRID 1981924 reaction equation
C1(N=[C:8]([OH:24])[C:9]2[C:10](=[CH:14][CH:15]=[CH:16][C:17]=2[C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=2)[C:11]([OH:13])=[S:12])C=CC=CC=1.[OH-:25].[Na+].Cl>>[C:18]1([C:17]2[CH:16]=[CH:15][CH:14]=[C:10]([C:11]([OH:13])=[S:12])[C:9]=2[C:8]([OH:24])=[O:25])[CH:19]=[CH:20][CH:21]=[CH:22][CH:23]=1

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 14798Sodium HydroxideHCID 178526135HCID 178526135, compound

Product 1

HCID 178524645HCID 178524645, compound

Conditions

Temperature
100 °C

Procedure

99.4 g (0.3 mol) of 3-phenylthiophthalic acid N-phenylimide are suspended in 1,326 ml of a 20% sodium hydroxide solution and the suspension is heated at 100° C. for 30 minutes, with stirring. After cooling, the alkaline suspension is acidified with 672 ml of 37% hydrochloric acid, with stirring. After one hour the fine suspension is filtered with suction, the material on the suction filter is suspended, whilst till wet, in 882 ml of 37% hydrochloric acid and the suspension is refluxed for one hour. The reaction mixture is cooled, the resulting fine suspension is filtered with suction and the product is dried at 80° C./13,000 Pa. 69.4 g (85 of theory) of 3-phenylthiophthalic acid are obtained.

Workup

  1. temperatureAfter cooling
  2. stirringwith stirring
  3. filtrationAfter one hour the fine suspension is filtered with suction
  4. filtrationthe material on the suction filter
  5. temperaturewhilst till wet, in 882 ml of 37% hydrochloric acid and the suspension is refluxed for one hour
  6. temperatureThe reaction mixture is cooled
  7. filtrationthe resulting fine suspension is filtered with suction
  8. customthe product is dried at 80° C./13,000 Pa

Sources & evidence

ORD record
ord-f99aeef4e3474831b4abdc6cbfa8790e
Source dataset
uspto-grants-1986_06
Patent number
US04594400

Reaction notes

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