Sulfuric Acid → HCID 13632604, compound

HRID 1982080Notes

Reaction equation

HRID 1982080 reaction equation
S(=O)(=O)(O)O.[NH2:6][C:7]1[CH:8]=[C:9]([N:13]2[C:18](=[O:19])[CH2:17][C:16]([CH3:21])([CH3:20])[CH2:15][C:14]2=[O:22])[CH:10]=[CH:11][CH:12]=1>C(OC(=O)CC)(=O)CC.O>[C:18]([NH:6][C:7]1[CH:8]=[C:9]([N:13]2[C:14](=[O:22])[CH2:15][C:16]([CH3:20])([CH3:21])[CH2:17][C:18]2=[O:19])[CH:10]=[CH:11][CH:12]=1)(=[O:19])[CH2:17][CH3:16]

Participants

5

Reactant 2

HCID 1118Sulfuric AcidHCID 233171371-(3-Aminophenyl)-4,4-dimethylpiperidine-2,6-dione

Product 1

HCID 13632604HCID 13632604, compound

Reagents, catalysts & solvents 2

HCID 31263Propionic anhydrideCatalystHCID 962WaterSolvent

Procedure

Five and one-half g. of propionic anhydride containing one drop of concentrated sulfuric acid was added to 9.3 g. of N-(m-aminophenyl)-3,3-dimethyl glutarimide in a small beaker. The mixture became warm and liquified. Upon cooling, the reaction mixture solidifed and was treated with water, collected by filtration and dried. Yield was 10.7 g. of a product having a m.p. of 199°-203° C. The product was identified as the title compound by analysis of infrared spectra.

Workup

  1. temperatureThe mixture became warm
  2. temperatureUpon cooling
  3. filtrationcollected by filtration
  4. customdried

Sources & evidence

ORD record
ord-8ca02bb7c74a4bdea62e778fb2ca4da7
Source dataset
uspto-grants-1986_06
Patent number
US04595408

Reaction notes

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