5-Methyl-3-(o-nitrobenzyl)-1,2,4-triazole → HCID 23317337, compound

HRID 1982129Notes

Reaction equation

HRID 1982129 reaction equation
[CH3:1][C:2]1[NH:6][N:5]=[C:4]([CH2:7][C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][C:9]=2[N+:14]([O-])=O)[N:3]=1>[Pd].C(O)C>[NH2:14][C:9]1[CH:10]=[CH:11][CH:12]=[CH:13][C:8]=1[CH2:7][C:4]1[N:3]=[C:2]([CH3:1])[NH:6][N:5]=1

Participants

4

Reactant 1

HCID 139262845-Methyl-3-(o-nitrobenzyl)-1,2,4-triazole

Product 1

HCID 23317337HCID 23317337, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 702EthanolSolvent

Procedure

A mixture of 1.67 g of 5-methyl-3-(o-nitrobenzyl)-1,2,4-triazole, 42 mg of 10% palladium on charcoal and 15 ml of ethanol is hydrogenated at 3 atmospheres pressure for 4 hours, filtered, decolorized, evaporated to a small volume and diluted with ether to give 3-(o-aminobenzyl)-5-methyl-1,2,4-triazole, m.p. 143°-145°.

Workup

  1. filtrationfiltered
  2. customevaporated to a small volume
  3. additiondiluted with ether

Sources & evidence

ORD record
ord-0ca15b9698c542778be6dfcca25b89c6
Source dataset
uspto-grants-1986_06
Patent number
US04595535

Reaction notes

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