Hydrochloric Acid → HCID 20149582, compound

HRID 1982157Notes

Reaction equation

HRID 1982157 reaction equation
[C:1]1([C:7]2[O:8][CH2:9][CH:10]([CH2:12][S:13]([C:15]3[CH:20]=[CH:19][C:18]([OH:21])=[CH:17][CH:16]=3)=[O:14])[N:11]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[ClH:22].C([OH:25])C>>[ClH:22].[C:7]([O:8][CH2:9][CH:10]([NH2:11])[CH2:12][S:13]([C:15]1[CH:20]=[CH:19][C:18]([OH:21])=[CH:17][CH:16]=1)=[O:14])(=[O:25])[C:1]1[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 702EthanolHCID 13686104HCID 13686104, compound

Product 1

HCID 20149582HCID 20149582, compound

Procedure

1.3 g (4.3 mM) of the oxazoline from Example 2 was dissolved in 30 mL ethanol and treated with 8 mL lN HCl for 3 hours. The solvents were removed under reduced pressure and the resulting foam was dried under high vacuum for 18 hours at 50° C. to give the title compound.

Workup

  1. customThe solvents were removed under reduced pressure
  2. customthe resulting foam was dried under high vacuum for 18 hours at 50° C.

Sources & evidence

ORD record
ord-83d3e80930a14554a563754178f7d2cb
Source dataset
uspto-grants-1986_06
Patent number
US04595687

Reaction notes

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