反应详情

Benzylisocyanate (13.3 g) is added dropwise to a stirred mixture of nitromethane (160 ml) and 15% fuming sulfuric acid (5.4 ml) at about 10° C. The reaction mixture is refluxed for about one hour, cooled to RT and the solid filtered and washed with nitromethene. The solid is suspended in ether, filtered, dried and used as a crude solid in the next step.

1. temperatureThe reaction mixture is refluxed for about one hour
2. filtrationthe solid filtered
3. washwashed with nitromethene
4. filtrationfiltered
5. customdried